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BIOLOGY APPLIED TO MEDICAL STUDIES (025ME-3)

A.Y. 2020 / 2021

Professor 
Period 
First semester
Credits 
2
Duration/Length 
20
Type of Learning Activity 
Core subjects
Study Path 
[PDS0-2017 - Ord. 2017] common
Syllabus 
Teaching language 

Italian

Learning objectives 

Knowledge and understanding. The student will learn the structure and function of the animal cell, and fundamental principles of genetics. The student will also learn principles regulating cellular interactions with other cells in tissues.
Ability to apply knowledge and understanding. With the acquired knowledge of cell biology, the student will have the necessary background for subsequent studies in the fields of physiology, anatomy, and general pathology.

Prerequisites 

This course requires basic knowledge of inorganic and organic chemistry, and rudiments of thermodynamics.

Contents 

This module, part of the Integrated course of applied Biomedical Sciences for first year students of the degree in Dental Hygiene, aims to provide basic notions on cellular and molecular biology; these include the processes of replication and expression of genetic information, and the organization and function of the cell.
Contents:
Chemical Components of Cells and biological macromolecules. DNA and Chromosomes. DNA Replication and Repair. From DNA to Protein: How Cells Read the Genome. The cell as fundamental unit. Membrane Structure. And function of membranes. Transport Across Cell Membranes. Intracellular Compartments and organelle functions. The cytoskeleton. Cell Signaling. The Cell Division Cycle, Mitosis, Meiosis. Cell cycle regulation, cell death, and cancer.

Teaching format 

The course is based on classroom lectures. At the end of each lecture, slides and presentations are readily accessible to students through the platform Moodle.
Any changes to the above procedure that might be necessary due to the COVID-19 emergency, will be published on the Department and the Course websites.

Extended Programme 

Macromolecules in the cell. Protein Structure and Function. DNA and Chromosomes. DNA structure. Structure of eukaryotic chromosomes. Chromatin organization. DNA Replication. DNA Repair. Definition of gene. Principles of gene expression. Transcription. Translation.
The cell. Membrane structure and membrane proteins. Transport Across Cell Membranes. Cellular organelles. Nucleus, mitochondria, lysosomes, peroxisomes. Endoplasmic reticulum, Golgi apparatus, exocytosis, endocytosis, vesicular traffic. Cytoskeleton. Intermediate filaments. Microtubules. Actin filaments. The Cell Division Cycle. Control of the cell cycle. Mitosis. Meiosis.
Cell Signaling. Ligands, receptors, and general principles of signal transduction. Cell death, apoptosis and necrosis. Cancer and cell transformation. Oncogenes and tumor-suppressor genes.

End-of-course test 

Written examination. The written exam includes multiple choice questions and open-ended questions on all contents of the course. In addition to assessing the specific knowledge of the subject, this test also evaluates the capacity to communicate such knowledge clearly and concisely.
Any changes to the above procedure that might be necessary due to the COVID-19 emergency, will be published on the Department and the Course websites.

Other information 

nothing

Texts/Books 

“Essential cell biology” Alberts et al. (Garland Science)
“The cell. A molecular approach.” Cooper e Hausman (Sinauer)
“Biologia cellulare e Genetica. Prima parte: Biologia Cellulare.” Fantoni et al. (Piccin)


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